THE CLINICAL SIGNIFICANCE OF TUMOR MARKERS COMBINATION MEASUREMENT IN DIAGNOSIS OF LUNG CANCER
- VernacularTitle:肿瘤标记物联合检测对肺癌诊断的价值
- Author:
Bingxiang YU
;
Bin HU
;
Liang′An CHEN
;
- Publication Type:Journal Article
- Keywords:
lung neoplasms;
biological markers;
diagnosis
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the clinical significance of combined measurement of neuron specific enolase(NSE), carcinoembryonic antigen(CEA) and Cytokeratin19 fragment 21 1 (CYFRA 21 1 ) in the diagnosis of lung cancer. The serum levels of CEA, NSE, and CYFRA 21 1 in 75 lung cancer patients as well as in 22 benign pulmonary diseases patients were measured by radioimmunoassay. Patients with pulmonary adenocarcinoma had a highest CEA level. Small cell lung carcinoma (SCLC) patients had a highest NSE level, while patients with squamous cell carcinoma of lung had a highest CYFRA 21 1 level. The positive rate of the combination of CEA, NSE, and CYFRA 21 1 for lung cancers was 82 67%. The results suggested that the combined measurement of CEA, NSE, and CYFRA 21 1 was helpful in the diagnosis of lung cancer.
