Platelet-activating factor and its receptor related with skin inflammation
- VernacularTitle:血小板活化因子及其受体与皮肤炎症
- Author:
Li JING
;
Jinhong HU
;
- Publication Type:Journal Article
- Keywords:
platelet activating factor(PAF);
PAF receptor;
skin inflammation
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Platelet activating factor(PAF), a potent phospholipid mediator of inflammation, has diverse physiological actions and participates in many diseases in vivo . In recent years, it has been revealed that PAF system involve in the expression of keratinocytes function and reaction of skin inflammation. Therefore, PAF system was found closely associated with inflammatory skin disease. Keratinocytes could express functional PAF receptors (PAF R) and involve in the action of epidermis cytokine system. The interaction between PAF system and other inflammatory mediators can lead to skin inflammatory cascade.
