Removal effect of non-bioartificial liver on the blood endotoxin and cytokines of hepatic failure patients
- VernacularTitle:非生物型人工肝对肝衰竭患者内毒素及细胞因子的清除作用
- Author:
Zewen WANG
;
Yingjie WANG
;
Bingwei LUO
;
Yuming WANG
;
- Publication Type:Journal Article
- Keywords:
hepatic failure;
plasma perfusion;
plasma exchange;
endotoxin;
cytokine
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the abilities of plasma perfusion and plasma exchange to remove blood endotoxin and cytokines from hepatic failure patients. Methods Plasma perfusion and plasma exchange were performed on 7 cases and 10 cases for the treatment of chronic severe hepatitis, respectively. Changes of blood endotoxin and cytokines before and after treatment were analyzed. Results The levels of cytokines and endotoxin in patient blood decreased greatly, but bilirubin decreased slightly after treatment with plasma perfusion. The changes of interleukin 6 were very limited. Compared with plasma perfusion, the removal of bilirubin was higher but that of cytokines was lower after plasma exchange. Conclusion Plasma perfusion can remove cytokines with high efficiency and retard the development of hepatic failure.
