The gene expressions of collagen types Ⅰ and Ⅲ in obstructive low compliant bladder in rats
- VernacularTitle:大鼠低顺应性膀胱中Ⅰ型和Ⅲ型胶原蛋白的基因表达
- Author:
Nan LIU
;
Bo SONG
;
Xiyu JIN
;
Enqing XIONG
;
- Publication Type:Journal Article
- Keywords:
low compliant bladder;
bladder outlet obstruction;
collagen;
mRNA
- From:Journal of Third Military Medical University
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the gene expressions of collagen types Ⅰ and Ⅲ in obstructive low compliant bladder in rats. Methods The expressions of collagen types Ⅰ and Ⅲ mRNA in rat bladder tissues were detected by in situ hybridization. Results Compared with those in the normal control, the gene expressions of collagen types Ⅰ and Ⅲ in smooth muscle of low compliant bladder were up regulated. Type Ⅲ gene expression was more obvious than type Ⅰ. Conclusion The expressions of collagen types Ⅲ and Ⅰ in obstructive low compliant bladder in rats are up regulated, which is related with low compliant bladder after obstruction.
