EFFECTS OF CRUDE AND PURIFIED POLYSACCHARIDE FROM GRIFOLA FRONDOSA ON TUMOR GROWTH AND IMMUNEFUNCTION IN MICE
- VernacularTitle:灰树花多糖粗品与纯品的抗肿瘤作用和对免疫功能的影响
- Author:
Xiaoding LI
;
Moucheng WU
;
Xiaobo ZENG
;
Jianhua RONG
;
- Publication Type:Journal Article
- Keywords:
Grifola frondosa;
polysaccharide;
anti tumor;
immune function
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the anti tumor activity and immune enhancing effect of crude(PGF) and purified (PGF 1) polysaccharide from Grifola frondosa. Methods:S 180 bearing mice were used as animal model. The effects on tumor weight and immune function were investigated. Results:PGF and PGF 1 showed inhibitory activity on S 180 growth. They could also increase weight of immune organs and improved the phagocytic function, DTH response, lymphocyte proliferation, antibody formation in splenic cells and content of serum HC IgM markedly. PGF was better than PGF 1. Conclusion:Both PGF and PGF 1 can inhibit S 180 tumor growth and enhance immune function in S 180 bearing mice.
