EFFECT OF RUBUSOSIDE EXTRACTS ON HYPERGLYCEMIC RATS INDUCED BY STREPTOZOTOCIN
- VernacularTitle:甜茶素提取物对STZ致高血糖大鼠的降血糖作用研究
- Author:
Cuiping TIAN
;
Weijing QU
;
Bin SUN
;
Mingjuan LI
;
Hong WANG
;
Xiaoqing HUNG
;
- Publication Type:Journal Article
- Keywords:
rubusoside extraction;
streptozotocin;
hyperglycemic rat;
Insulin
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the anti hyperglycemic effect of rubusoside on diabetic rats induced by streptozotocin (STZ)and its mechanism . Methods: The STZ induced diabetic rats were dived into three groups and were given (ig.) saline, rubusoside and Phenformin respectively once a day. After three weeks, the levels of serum glucose, fructosamine, insulin,SOD were assayed. Results: Rubusoside could reduce the level of serum glucose significantly, enhance the ability of anti oxidation and stimulate the secretion of insulin in STZ induced diabetic rats. Conclusion: The action of rubusoside on secretion of insulin can be explained for the anti hyperglycemic effect.