Genetically engineered mice in post-genomics era
- VernacularTitle:后基因组时代的基因工程小鼠
- Author:
Yiping HU
;
Yitao ZENG
;
- Publication Type:Journal Article
- Keywords:
genetically engineered mice;
transgenic mice;
gene knockout mice;
gene knockin mice
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Genetically engineered mice is one of the powerful research systems in exploring the gene protein life phenomenon,which is useful in generating the laboratory animal model of human diseases and developing the new drugs. With the development of functional genomics and model organism in life science area, biological medicine research is in need of genetically engineered mice deadly. There are still some problems to be resolved, including death effect, no or low expression and no phenotype. It is essential to improve the basic research related to genetically engineered mice.
