Study on diagnosis of irritable bowel syndrome
- VernacularTitle:肠易激综合征的临床诊断研究
- Author:
Dingguo LI
;
Jianxin WU
;
- Publication Type:Journal Article
- Keywords:
irritable bowel syndrome;
diagnosis
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
There are no anatomic or physiologic criteria for the diagnosis of irritable bowel syndrome (IBS) and the disease is defined mainly on exclusion of organic lesions. Therefore, quite a few patients with IBS are not promptly diagnosed and treated. It is important to apply RomeⅡCriteria, instead of its limitation, in those who have abdominal pain with relief by defecation, sensation of incomplete evacation after defacation, passage of rectal mucus and abdominal distention, and to employ endoscope and laboratory studies necessary for those with "red flags" to exclude organic diseases. Recent advances in the research of IBS demonstrated that predisposing factors such as intestinal inflammation may contribute to changes in the intestinal mucosal immune system, resulting in hypersensitivity of afferent nerves and abnormal intestinal motility. Severe life events or/and chronic depression are more likely to associate with the patterns of IBS and its severity, and to have relation with post infection IBS. Behind the above mentioned factors there may exist specific genetic abnormality.
