Intermittent positive pressure ventilation in treatment of pulmonary edema after seawater drowning in rabbits
- VernacularTitle:间歇正压通气治疗兔海水淹溺型肺水肿
- Author:
Zhihai HAN
;
Yunyou DUAN
;
Hongwu WANG
;
- Publication Type:Journal Article
- Keywords:
intermittent positive pressure ventilation;
pulmonary edema;
seawater drowning
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the therapeutical effect of intermittent positive pressure ventilation (IPPV) on pulmonary edema after seawater drowning in rabbits.Methods:Fourteen seawater lavage induced pulmonary edema New Zealand rabbits models were assigned to receive IPPV treatment.Blood gas analysis, pulmodynamics, hemodynamics status and serum tumor necrosis factor(TNF ?) were monitored at various time points.After 3 h ventilation rabbits of each group were killed to gain lung tissues for pathology examination, and lung lavage fluid was analyzed to count leukocytes.Results:PaO 2 significantly increased after the use of ventilation in pulmonary edema rabbits models ( P
