Research on apurinic/apyrimidinic endonuclease/redox-factor 1
- VernacularTitle:无嘌呤无嘧啶核酸内切酶/氧化还原因子1的研究进展
- Author:
Liang FENG
;
Fuyuan SHAO
;
- Publication Type:Journal Article
- Keywords:
apurinic/apyrimidinic endonuclease/redox factor 1;
review literature
- From:
Academic Journal of Second Military Medical University
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Apurinic/apyrimidinic endonuclease/redox factor 1(APE/Ref 1) is a multifunctional protein that is responsible for repairing DNA damage,it also infleunce reduction oxidation (redox) reaction and modulate the DNA binding activity of transcription factors,it is important to cell survival.Recently, much data concerning APE1/Ref 1 and information on APE1/Ref 1 in a wide variety of functions and systems have rapid growth,including its gene,function,distribution and relations with some diseases,especially nervous system diseases and tumors.
