Effect of fengliao changweikang granule on SOD and MDA in blood of rats with cellular immunoreactive colitis
- VernacularTitle:枫蓼肠胃康颗粒对细胞免疫反应性结肠炎中SOD、MDA的影响
- Author:
Jian FU
;
Shaoyi KUANG
;
Peiqong LI
;
Guilan XIN
;
- Publication Type:Journal Article
- Keywords:
fengliao changweikang granule;
celluar immrnoreactive colitis;
oxygen free radical;
experimental study
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the influence on change of SOD and MDA in the blood of rats which had cellular immunoreactive colitis by Fengliao Changweikang Granule (CWKG). METHODS Male Wistar rats were divided into six groups. Numbers of each group were 32. Animal model of rat cellular iumynoreactive colitis was made by TNBS and ethanol mixed liguid enema. Rats were killed at the 1st, 3rd, 7th and 21st day respectively. Gross morphologic observation of intestinal wall was made, SOD vitality and MDA content in blood were determined. RESULTS At day 7 and 21, the intestinal wall damage criterion value of large dosage group was lower than model group ( P
