EFFECT OF PAPAVERINE ON CEREBRAL VASOSPASM FOLLOWING CEREBRAL ANEURYSM OPERATION
- VernacularTitle:罂粟碱对于防治脑动脉瘤术后脑血管痉挛的临床研究
- Author:
Jun WANG
;
Jing′An ZHOU
;
Ce LIU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
papaverine;
vasospasm, intracranial;
intracranial aneurysm;
subarachnoid hemorrage
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the effect of papaverine administered via different routes following cerebral aneurysm operation, 43 cerebral aneurysm patients were divided randomly into two groups: A and B. Patients of group A were placed with a silicagel tube in cerebral ventricle and lavaged repeatedly with papaverine solution during operation and following 3 days after operation, those of group B were intramuscularly injected with papaverine 30mg, 3 times per day,for one week. By analysis of clinical features and TCD data, both A and B could cure cerebral vasospasm, but group A was obviously superior to group B. Our conclusion is that papaverine solution lavaged locally can effectively prevent cerebral vasospasm after cerebral aneurysm operation .
