Morphologic colonic adaptation following total small bowel resection in the rat
- VernacularTitle:全小肠切除大鼠结肠代偿性增生
- Author:
Wenchuan WU
;
Dayong JIN
;
Yanyan ZHANG
;
- Publication Type:Journal Article
- Keywords:
Total small intestine resection;
Colonic adaptation;
Enteral nutrition;
Rat
- From:
Parenteral & Enteral Nutrition
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To investigate the morphologic changes of the colon in the rats after a total small bowel resection. Methods:Ten male Sprague Dawley(350～370 g) rats in the experimental group were undergone resection of total small bowel,and ten normal rats were randomly chosen as the control group.After supported by enteral nutrition for 3 months,rats were sacrificed and the colon harvested for morphologic parameters study. Results:The length,diameter,wet weight,crypt depth,mucosal thickness and kerckring height of the colon in the experimental group were significantly higher than those in the control group( P
