Endothelial cell and angiogenesis
- VernacularTitle:内皮细胞与血管形成
- Author:
Lizhi ZHAO
;
Rifang YANG
;
Hai WANG
;
- Publication Type:Journal Article
- Keywords:
angiogenesis;
endothelial cell;
angiogenic factors;
target
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Recent evidence suggests that, in spite of the redundancy of angiogenic factors involved in pathological angiogenesis , strategies aimed at inhibiting specific endothelial cell angiogenic factors at their release or receptor level may form the basis for effective and safe treatment of angiogenic mediated disease processes. Physiologic angiogenesis is fundamental to reproduction, development and repair. Pathological angiogenesis sustains the progression of many neoplastic and proinflammatory diseases. And endothelial cell is an important target especially for the angiogenesis. The target represents a novel strategy for the treatment of the human disorders where pathological angiogenesis is involved.
