Effect of Icarrin on cGMP levels in penile corous cavernosum of rabbit
- VernacularTitle:淫羊藿苷对家兔阴茎海绵体cGMP浓度的效果
- Author:
Jie FU
;
Liang QIAO
;
Taiyi JING
;
Guiting LIN
;
Yinye WANG
;
Zhongcheng XIN
;
- Publication Type:Journal Article
- Keywords:
cGMP;
corpus cavernosum;
icarrin;
erection
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the effect of Icarrin on penile erection and cyclic GMP levels in rabbit corpus cavernosum(RCC). METHODS Effects of various concentration of Icariin on cGMP level in RCC were measured by 125 I radioimmunoassay procedure with Sildenafil and papaverine as the positive controls RESULTS In the presence of SNP, Icariin increased cGMP concentration in rabbit corpus cavernosum in a dose dependent manner ( P