Effect of bartroxobin on adhesion molecule expression in peripheral blood of patients with acute ischemic stroke
- VernacularTitle:巴曲酶对急性缺血性脑卒中患者外周血中黏附分子表达的影响
- Author:
Bin XIA
;
Zhongxin ZHAO
;
Lingzhen ZHANG
;
Fuyuan SHAO
;
- Publication Type:Journal Article
- Keywords:
bartroxobin;
brain ischemia;
stroke;
adhesion molecule
- From:
Academic Journal of Second Military Medical University
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the expression changes of adhesion molecules in peripheral blood leukocytes and serum soluble adhesion molecules in acute ischemic stroke after treatment with bartroxobin. Methods:Treatment group( n =8) was given bartroxobin (20 BU in 3 d) and other routine treatment;Control group( n =18) was similar to treatment group except for bartroxobin.The expression of CD11b,CD18,CD62L,CD54 on polymorphonuclear and monocyte were measured by flow cytometry, soluble ICAM 1 and VCAM 1 were measured by enzyme linked immunosorbent assay in consecutive patients[within 12,24,48 h( P
