TRAIL and its receptor expression in activated lymphocytes
- VernacularTitle:激活淋巴细胞中TRAIL及其受体表达的初步研究
- Author:
Junjie JI
;
Lixin WEI
;
Xiaodong LI
;
Mengchao WU
;
Yajun GUO
;
- Publication Type:Journal Article
- Keywords:
tumor necrosis factor related apoptosis inducing ligand;
phytohemagglutinins;
polymerase chain reaction;
sequence analysis,DNA;
lymphocytes
- From:
Academic Journal of Second Military Medical University
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression difference of TRAIL and its receptors between resting and activated peripheral blood lymphocytes, and to study their role in cellular growth and proliferation. Methods: Expression of TRAIL and its receptors were detected by RT PCR and DNA sequencing. Results: Neither the expression of TRAIL nor its receptors were detected in resting peripheral blood lymphocyte. However, both expression were found in activated peripheral blood lymphocytes of various degree. Conclusion: TRAIL and its receptors may play a role in regulation and control of the activated lymphocytes in immune reaction.
