Pathological significance and mechanism of advanced glycation end-products
- VernacularTitle:晚期糖基化终产物的病理意义及其机制
- Author:
Mianen SUN
;
Guanhua DU
;
- Publication Type:Journal Article
- Keywords:
AGEs, Maillard reaction, diabetes, aging
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Advanced Glycation End products (AGEs) are the products of non enzymatic glycationprotein. It has been demonstrated that AGEs are closely correlated to a variety of diseases such as diabetes,vascular complications,aging and renal diseases. AGEs play important roles in the development of these diseases. They can effect the function of cells and tissues directly, and also mediate pathological reactions through binding with special receptors. The present paper reviews the procedures of AGEs production,action mechanism and pathology of AGEs.
