Research development on the Immumodulatory effect of polysaccharide and its mechanism
- VernacularTitle:免疫活性多糖的免疫调节作用及机制研究进展
- Author:
Hongliang CHEN
;
Botao LI
;
Jiaxiang ZHANG
;
Defa LI
;
Biying CHANG
;
Longtao XU
;
- Publication Type:Journal Article
- Keywords:
polysaccharides;
immunomodulation;
gene expression;
receptor;
signal transduction
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharides are important large molecules in the body. It has many functions such as activting the lymphocytes like T,B, NK and M? cells, promoting the secretion of cytokines and antibodies through binding to the CR 3 receptor of lymphocytes, affecting the concentrations of cellar [Ca 2+ ] i, cAMP, cGMP, NO and PGE 2, and promoting the gene expression of cytokines. Its function also relate to its molecule weight and structure.
