Effect of esculentoside A on apoptosis of mouse thymocyte
- VernacularTitle:陆皂苷甲对小鼠胸腺细胞凋亡的影响
- Author:
Zhenyu XIAO
;
Qinyue ZHENG
;
Xiangmin ZHENG
;
Minghe CHENG
;
Yanghua YI
;
- Publication Type:Journal Article
- Keywords:
esculentoside A;
thymocyte;
apoptosis
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of esculentoside (EsA) on apoptosis of murine thymocyte. Methods:Using electronic microscope, DNA agarose electrophoresis and flow cytometry analysis,the effect of EsA on apoptosis of murine thymocyte was examined. Results:The result showed that apoptosis of activated thymocyte by ConA was markedly promoted by 2.5, 5, 10 ?g/ml EsA in murine thymocyte culture for 3 h, but the spontaneous apoptosis was not affected by EsA. Conclusion:The results suggest that EsA has the positive effect on apoptosis of activated murine thymocyte.
