Effect of endometriosis peritoneal fluid on natural killer cell activity of normal people
- VernacularTitle:子宫内膜异位症患者腹腔液对正常NK细胞活性的抑制及相关因素分析
- Author:
Wen LI
;
Yan LIU
;
Zhijun JIN
;
Siqi DING
;
- Publication Type:Journal Article
- Keywords:
endometriosis;
killer cells, natural;
prostaglandin;
interleukin 6
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of the peritoneal fluid (PF) in women with endometriosis (EM) on the natural killer (NK) cell activity, and to study its relationship with the level of prostaglandins(PGs) and interleukin 6(IL 6). Methods:HeLa cells were taken as target cell, the LDH releasing assay was used to measure NK cell activity after preincubation with PF of EM. The concentration of IL 6, PGE 2 and PGF 2? was measured by radioimmunoassay. Results:After incubated with PF of women with and without EM for 2 h, the inhibition percentages was(65.2?21.8)% and (37.1?18.9)% respectively ( P
