Clinical evaluation of the effect of perindopril alone and combined with gliclazide in the treatment of diabetic nephropaphy
- VernacularTitle:培哚普利单用和与格列齐特联用治疗糖尿病肾病的临床疗效评价
- Author:
Xiaodong ZHANG
;
Xinli LI
;
Quncai LIU
;
- Publication Type:Journal Article
- Keywords:
nephropaphy;
nifedipine;
perindopril;
urine minim albumin
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observed clinical effect and safety of perindopril alone and combined with gliclazide in the treatment of type Ⅱ diabetic with hypertension and diabetic nephropaphy (DN). METHODS: 61 patients (male 34, female 27) were randomly divided into 2 groups. Perindopril group (n=31): perindopril 4 mg qd, and gliclazide 80 mg bid. Nifedipine group (n=30): nifedipine 10 mg qd, and gliclazide 80 mg bid. The treatments lasted for three months. RESULTS: After the treatments, the levels of blood pressure, FPG, and GHb were distinctly reduced in the two groups (P0.05). In perindopril group, the urine minim albumin (UMA) was markedly reduced (P
