Total Body Irradiation in Leukemia: Preliminary Report.
- Author:
Hong Seok JANG
1
;
Su Mi CHUNG
;
Ihl Bohng CHOI
;
Choon Yul KIM
;
Yong Whee BAHK
;
Choon Choo KIM
;
Dong Jip KIM
;
Jae Soo LEE
Author Information
1. Department of Radiology, Catholic University Medical College, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Total body irradiation;
Leukemia;
Bone marrow transplantation
- MeSH:
Bone Marrow Transplantation;
Diarrhea;
Humans;
Leukemia*;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive;
Mucositis;
Nausea;
Particle Accelerators;
Pneumonia;
Radiation Oncology;
Skin;
Transplants;
Vomiting;
Whole-Body Irradiation*
- From:Journal of the Korean Society for Therapeutic Radiology
1988;6(2):247-252
- CountryRepublic of Korea
- Language:English
-
Abstract:
Total body irradiation has been applied to treat acute leukemia and chronic granulocytic leukemia. 20 patients with acute leukemia or chronic granulocytic leukemia were treated with total body irradiation using 6 MV linear accelerator before bone marrow transplantation at the Division of Therapeutic Radiology, department of Radiology, St. Mary's Hospital, catholic University Medical College from August 1987 to September 1988. Among 20 patients, 8 patients received 6 fractions of 200 cgy (total 1200 cgy), 10 patients received a single 850 cgy radiation, 1 patient received 4 fractions totaling 850 cgy (200, 200, 200, 250), and 1 patient received 1100 cgy in 2 fractions (850, 250). 17 patients received allogenic grafts, 2 patients received autologous grafts, and only one patients received one locus mismatched graft. 13 patients are still alive and 7 patients died. The complications induced by total body irradiation were nausea and vomiting, diarrhea, skin eruption, mucositis, and pneumonitis.
