Protective effects of N~6-cyclohexyladenosine on neural function after brain trauma in rats
- VernacularTitle:环己基腺苷对大鼠脑损伤后神经功能的保护作用
- Author:
Wusong TONG
;
Yicheng LU
;
Jiyao JIANG
;
Cheng ZHU
;
- Publication Type:Journal Article
- Keywords:
brain injuries;
neural function;
N 6 cyclohexyladenosine
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of adenosine A 1 receptor agonist N 6 cyclohexyladenosine(CHA) on neurofunction after fluid percussion injury in rats. Methods: The effects of CHA intra cerebroventricular injection 10 min before brain trauma on rats neurofunction and neuropathological changes were evaluated. Results: Compared with the control group, CHA could ameliorate the behavior deficits and improve pathological change. Conclusion: Adenosine A 1 receptor plays an important neuroprotective role in rat secondary injuries following brain trauma.
