Urapidil and nitroglycerine for the control of cardiovascular responses to tracheal intubation/extubation in patients with essential hypertension
- VernacularTitle:高血压病人气管插管 /拔管期心血管反应的药物控制
- Author:
Xiaoqing CHAI
;
Kunzhou CHEN
;
- Publication Type:Journal Article
- Keywords:
urapidil;
nitroglycerine;
intubation;
extubation;
cardiovascular responses
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effectiveness of urapidil and nitroglycerine on controlling the cardiovascular responses to tracheal intubation/extubation in patients with essential hypertension. METHODS: 45 patients with essential hypertension undergoing general anesthesia were divided randomly into control (C, without depressor, n=15), urapidil (U, 0.5 mg?kg -1 , n=15), and nitroglycerine (N, 1 ?g?kg -1 , n=15) groups. The SBP, DBP, MAP, HR and RPP were measured during intubation and extubation and at the induction of anesthesia and the end of operation respectively. RESULTS: The SBP, DBP, MAP, HR and RPP increased markedly (P
