Methods in analysis of the dynamics of drug interaction and its software CoDrug
- VernacularTitle:药物相互作用动力学分析方法及其CoDrug软件
- Author:
Qingshan ZHENG
;
Ruiyuan SUN
;
- Publication Type:Journal Article
- Keywords:
drug interaction;
combination drug therapy;
drug synergism;
drug antagonism
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
In clinical and experimental therapeutics, the quantitative analysis of drug interaction will supply a tool for optimizing and evaluating a combination in the study of compound drug, the design of combination drug therapy, and the evaluation of traditional medicine formulae. This paper listed the systematic methods of the quantitative analysis, including the weighted modification method for optimizing constituents, doses and ratio in combination, the parameter method and the reflection method for dynamic analysis of drug interaction, and a comprehensive method for multiple response indexes. The software CoDrug about these methods also was introduced.
