Evaluation of endothelium function in left anterior descending coronary artery by transesophageal echocardiography in subjects with angiographically normal coronary arteries
- VernacularTitle:食管超声心动图评价冠脉造影正常者的冠脉内皮功能
- Author:
Ping FANG
;
Zuo HUANG
;
Min FAN
;
Xiaotao WANG
;
Xiaoping NIU
;
- Publication Type:Journal Article
- Keywords:
coronary disease;
coronary vessels;
endothelium,vascular;
echocardiography,transesophageal
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a mini invasive way to evaluate endothelium function. Methods: Group 1 consisted of 10 subjects with no risk factors for coronary artery disease, group 2 consisted of 11 subjects with risk factors for coronary artery disease and angiographically normal coronary arteries. Two groups of patients underwent transesophageal echocardiography(TEE) for assessment of LAD diastolic blood flow velocity (V) and time velocity integral (VTI) at rest (B 1), 2 min after immersion of the hand in cold water (CPT), 5 min after rewarming of the extremity (B 2), and 5 min after administered nitroglycerin. The percent change in V and VTI were calculated between B 1 and CTP and B 2 and nitroglycerin. Results: After CPT the percent increase in V and VTI were significant in group 1 than group 2 ( P