The expression and function of potassium channel in microglia
- VernacularTitle:小胶质细胞钾通道的表达与功能
- Author:
Chongbo ZHONG
;
Xiaoliang WANG
;
- Publication Type:Journal Article
- Keywords:
Microglia;
potassium channel;
Alzheimers disease
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Microglia are immunocells in the brain and play key roles in the chronic inflammation of Alzheimers disease. Potassium channels are the important pathway for the microglia response to thechanges of microcircumtance in the brain. And the changes of potassium channels are the important marker of the activated microglia. The potassium channels are involved in the normal and pathological functions of microglia such as maintaining the membrane potential, proliferation, ramification, and the respiratory burst.
