Role of Arsenic Trioxide Anti-tumor and Its Mechanism
- VernacularTitle:三氧化二砷的抗癌作用及其机制的研究进展
- Author:
Zhishen ZHAO
;
Congxin HUANG
;
- Publication Type:Journal Article
- Keywords:
arsenic trioxide;
cell apoptosis;
tumor
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
As a drug, arsenic trioxide is effectively used for acute promyelocytic leukemia clinically. Inducing tumor cell apoptosis is one of its major mechanism via bcl 2 gone. Therefore, arsenic trioxide is tried in experimental studies on some tumors, such as chronic myelocytic leukemia, lymphoma and gastric carcinoma, even on prevention of restenosis after percutaneous transluminal coronary angioplasty.
