Chemopreventive effects of NSAIDs on colorectal cancer
- VernacularTitle:非甾体类抗炎药与大肠癌化学预防
- Author:
Qiao MEI
;
Jieping YU
;
- Publication Type:Journal Article
- Keywords:
NSAIDs;
colorectal cancer;
chemopreventions;
cyelooxgenase
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Many epidemiological data and study of experiment show that adminstration of NSAIDs in long term can prevent the carcinogenesis of colorectal cancer, its mecanism can be associated with the inhibition of PG which is produced by Cox 2 way, in addition, promoting apoptosis and anti oxidation were also one of the mecanisms of NSAIDs, the new selective Cox 2 inhibitor without gastrointestinal side effect would become the chemopreventive drugs of colorectal tumor.
