A clinical study of the use of MCT/LCT and LCT in neonatal infants with hepatic dysfunction
- VernacularTitle:新生儿肝功能障碍时不同脂肪乳剂对血脂和肝功能影响的比较研究
- Author:
Ying PING
;
Shaoming SONG
;
Junle WANG
;
Ye FENG
;
- Publication Type:Journal Article
- Keywords:
Neonate;
Hepatic dysfunction;
Fat emulsion;
MCT/LCT
- From:
Parenteral & Enteral Nutrition
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To compare the effect of different fat emulsions on the blood lipid and liver function in neonates with hepatic dysfunction. Methods:40 babies with hyperbilirubinemia(≥51.3 mmol/L) were randomly divided into two groups ,receiving the fat emulsion of 20% Intralipid (LCT group) or 20% Lipofundin (MCT/LCT group) at the dose of 2.0 g/(kg?d) for 7 days. Blood lipid 〔total cholesterol(TC), triglyceride(TG)〕 and the serum biochemical indexes relative to liver function were measured before and after the period of 7 days. Results:The levels of TC did not change remarkably in two groups. There was significant difference in the levels of TG between the two groups after the study period (1.87?0.3 mmol/L in LCT group and 1.15?0.27 mmol/L in MCT/LCT group, t =7.833, P