Enteral nutrition reduce pancreatic infection of severe acute pancreatitis in rats
- VernacularTitle:肠内营养减少大鼠急性重症胰腺炎继发感染
- Author:
Jun LIU
;
Zhengjun QIU
;
Zhihai PENG
;
Fuquan ZHONG
;
- Publication Type:Journal Article
- Keywords:
Enteral nutrition;
Severe acute pancreatitis;
Pancreatic infection
- From:Parenteral & Enteral Nutrition
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To investigate if enteral nutrition can reduce pancreatic infection of severe acute pancreatitis(SAP) in rats. Methods:32 SD rats were divided into 4 groups.SAP was induced in rats of A group and C group, and rats fo B group and D group underwent laparotomy without induction of SAP. A group and B group received total parenteral nutrition(TPN),and C group and D group received enteral nutrition(EN) beginning from the 3rd postoperative day.The samples of blood,MLN,pancreas,liver,kidney and lung were detected for bacteria at the end of the study.Blood sugar,albumin and amylase were also detected. Results:None of the rats died.The positive rates of bacteria cultures in MLN and pancreas were significantly lower in C group(37.5%) than those in A group(87.5%)( P =0.033).The species of cultured bacteria were mainly those seen in the gut. Conclusions:Enteral nutrition can reduce the pancreatic infection of severe acute pancreatitis in rats.
