Clinical analysis of intravenous infusion of fibrinolytic agent in the treatment of acute cerebral infarction
- VernacularTitle:尿激酶静脉溶栓治疗急性脑梗死临床分析
- Author:
Zhengshe BAO
;
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
urokinase;
thrombolytic therapy
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To evaluate the clinical efficacy and safety of thrombolytic therapy for acute cerebral infarction. Methods Twenty eight patients with acute cerebral infarction in the thrombotytic group were given an intravenous infusion of urokinase at the dose of 2 000 000 U and 30 patients received conventional therapy in the control group. Results Of the 28 cases, 4 recovered and 8 were markedly effective within 24 hours, while none of the 30 patients was effective. After 14 days, 12 patients in the thrombolytic group and one in the conventional therapy group cured. The effective rate in the thromblytic group was higher than that in the conventional therapy group. Statistical difference was found between the two groups. Conclusion Early intravenous thrombolytic therapy with urokinase shows remarkable efficacy for acute cerebral infarction.