EFFECTS OF GLYCOPROTEIN FROM CHLAMYS (AZUMAPECTEN) FARRERI ON TUMOR GROWTH AND IMMUNE FUNCTION IN MICE
- VernacularTitle:栉孔扇贝糖蛋白的肿瘤抑制活性和对免疫功能的影响
- Author:
Qianqun GU
;
Yuchun FANG
;
Xianliang XIN
;
Changyun WANG
;
- Publication Type:Journal Article
- Keywords:
Chlamys (Azumapecten) farreri;
glycoprotein;
tumor inhibition;
immune function
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the antitumor activity and immune enhancing effect of glycoprotein from Chlamys (Azumapecten) farreri (FGP). Methods: S 180 bearing mice were used as animal model. The effects of FGP on tumor weight and immune function were observed in S 180 bearing mice. Results: The results showed that FGP could markedly decrease tumor weight and promote the phagocytic rate of macrophages, NK activity and increase weight of immune organs. Conclusion: FGP can inhibit the growth of S 180 tumor and enhance cell mediated immune function. The antitumor effect of FGP may be related to its immune enhancing activity.
