EFFECT OF MAGNESIUM SUPPLEMENTATION ON LIPID PEROXIDATION AND ANTIOXIDATIVE ENZYMES
- VernacularTitle:镁对内皮细胞脂质过氧化和抗氧化酶的影响
- Author:
Xiaohua LU
;
Ruishu WANG
;
- Publication Type:Journal Article
- Keywords:
magnesium;
human umbilical vein endothelial cells;
lipid peroxidation;
antioxidant enzymes
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The effect of magnesium on lipid peroxidation of endothelial cells induced by H 2O 2 and t bultyl hydroperoxide and subsequent alterations of extracellular superoxide dismutase(EC SOD) and cellular selenium dependent and selenium independent GSH Px were studied. Methods:The extent of cellular lipid peroxides was determined by measuring the formation of TBARS, EC SOD by the method of pyrogallol auto oxidation, and GSH Px by the method of DTNB. Results:The results showed that the formation of TBARS was significantly reduced in the group of H 2O 2+Mg 2+ at doses of 0.3, 0.6, 1.2,and 2.4 mmol/L compared to the group of H 2O 2(P
