EXPRESSION OF INTERCELLULAR ADHESION MOLECULE-1 IN CORNEA OF RAT WITH BACTERIAL KERATITIS
- VernacularTitle:细胞间粘附分子-1在细菌性角膜炎角膜组织表达的实验研究
- Author:
Qinhua FAN
;
Minghua GUO
;
Canrong NI
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
intercellular adhesion molecule 1;
bacterial keratitis;
immunohistochemical staining
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the role of intercellular adhesion molecule 1(ICAM 1) in the pathogenesis of bacterial keratitis,22 rats were randomly divided into bacterial keratitis group and control group. A specific staining of corneal epithelial cells, stromal keratocytes and endothelial cells for ICAM 1 was carried out by using monoclonal antibody to ICAM 1 and immunohistochemical staining techniques. The results showed that ICAM 1 expressed a low level in the corneal epithelial cells, stromal keratocytes and endothelial cells in the control group(-~+), while its expression was strong in the keratitis group (~). The difference between two groups was statistically significant ( P
