The role of BN52021 in the hemodynamics in rat random skin flap
- VernacularTitle:银杏苦内酯B对大鼠任意皮瓣血供的影响
- Author:
Yanjie FU
;
Qifei XU
;
Yunxia MA
;
Zhifeng ZHANG
;
Xin XING
;
Minggen XIONG
;
- Publication Type:Journal Article
- Keywords:
surgical flaps;
antagonists and inhibitors;
platelet activating factor;
radionuclide imaging;
99m Tc
- From:
Academic Journal of Second Military Medical University
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the effect of platelet activating factor(PAF) antagonism on the blood content in the random survival flap. Methods: A lipophilic PAF receptor antagonist BN52021 was administered to treat flaps through a local subcutaneous injection route 30 min prior to transplantation. The flaps were imaged in situ by a gamma camera. Results: The PAF receptor antagonist significantly augmented the accumulation of radioactivity of middle and end part within treated flaps( P
