EXPERIMENTAL STUDY ON OSSEOINTEGRATION AND BONE FORMATION OF DENTAL IMPLANTS IN RATS WITH OSTEOPOROSIS
- VernacularTitle:骨质疏松状态下牙种植体骨整合及生长改变的实验研究
- Author:
Ya′Nan LI
;
Hongchen LIU
;
Ziyan NI
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
dental implants;
osseointegration;
osteoporosis;
rats
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
The aim of the study was to observe osseointegration of dental implants in osteoporotic rats. Rats were randomly divided into groups A(SHAM) and B(OVX), and pure titanium screws were implanted in the distal half of the right femurs. 1 5 and 3 months after implantation, half of the rats in each group were sacrificed and right femurs were observed by X ray photography, scan electron microscopy as well as light microscopy. The results showed that 1.5 and 3 months after implantation, the osseointegration index (OI) of group A was higher than that of group B. But the OI of each group was almost the same at different intervals. 1 5 months after implantation, the amount of new bone formation in group A was more abundant than that in group B, and it increased in group A but decreased in group B 3 months after implantation.The results confirmed that with higher BMD osseointegration was better. Osteoporotic changes could decrease OI and the amount of new bone formation at implant bone interface in rats. Osseointegration would not improve without outside factors.