THE HYPOGLYCEMIC EFFECT OF LAMINARINA JAPONICA POLYSACCHARIDES IN DIABETIC MICE
- VernacularTitle:海带多糖对糖尿病小鼠血糖的调节作用
- Author:
Tingxin WANG
;
Wen ZHAO
;
Dongsheng JIANG
;
Shuzhen QIN
;
Xiaotong MA
;
- Publication Type:Journal Article
- Keywords:
Laminarina Japonica Polysaccharides;
diabetes;
blood glucose
- From:
Acta Nutrimenta Sinica
1956;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the effect of Laminarina Japonica Polysaccharides (LJPS) on blood glucose in diabetes mice.Methods: Effect of LJPS on alloxan inducing diabetes mellitus model was investigated by applying different doses(125,250 and 500mg/kg bw).Results: The doses of LJPS were able to lower blood glucose level by 34.96%,20.70% and 26.82% respectively. They also decreased BUN level, enhanced liver glycogen, calcium in serum and insulin concentration. LJPS could restore the injury of alloxan induced pancreas islet significantly by histopathological findingConclusion: The results show that LJPS is an active component in protecting against alloxan induced pancreas injury and mediating the blood glucose level.
