THE PROTECTIVE EFFECT OF ?-CAROTENE IN ANOXIA-INJURED CARDIOMYOCYTES
- VernacularTitle:?-胡萝卜素对心肌细胞缺氧损伤的保护作用研究
- Author:
Li SHEN
;
Shen WANG
;
Fang XIE
;
Xuming ZHU
;
Pijing WEI
;
- Publication Type:Journal Article
- Keywords:
carotene;
cardiomyocyte;
anoxia
- From:
Acta Nutrimenta Sinica
1956;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the protective effect of ? carotene in anoxia injured cardiomyocytes. [WT5FZ]Methods: The cultured rat neonatal cardiomyocytes were subjected to 2h anoxia and the changes of lactate dehydrogenase(LDH) activity, malondialdehyde (MDA), oxygen free radical (OFR) contents and superoxide dismutase (SOD) activity were detected. The effects of pre treatment with ? carotene were then investigated. Results: The LDH, MDA, OFR and SOD of cardiomycytes were changed significantly after 2h anoxia (P
