Pathological observation of airway inflammation after neonatal CVB_3 inoculation in rats
- VernacularTitle:新生鼠呼吸道感染CVB_3致气道炎症的病理学观察
- Author:
Chaoping FANG
;
Feng FANG
;
Qian SHEN
;
Dalie MA
;
Hongxia WEI
;
Yulian XU
;
- Publication Type:Journal Article
- Keywords:
respiratory tract infecfions;
Coxsackievirus B;
pathology
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of coxsackie virus B 3 on airway tract and lung morphology, and to study the relation between CVB infection and asthma. Methods: We established CVB 3 infective model: 5 d neonatal rats inhaled CVB 3 by ultrasonic brume. CVB 3 IgM was examined 10 d after inoculating of CVB 3, and LW/BW, airway tract and lung pathological change 10 d and 30 d after inoculation of CVB 3 were observed. Results: Rats from the virus group had higher D of CVB 3 IgM than control's ( +2s ) and had higher LW/BW 10 d after inoculation of CVB 3 than control ( P
