Experimental study of the inhibitory effects of biotic royal jelly on the growth of ascitic hepatoma cell H_( 22) in mice
- VernacularTitle:生物蜂王浆抑制腹水型肝癌细胞H_(22)生长的实验研究
- Author:
Yongzi WANG
;
Changquan LING
;
Xueqiang HUANG
;
Pinrong PAN
;
- Publication Type:Journal Article
- Keywords:
biotic royal jelly;
liver neoplasms;
drug therapy
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the inhibitory effects of biotic royal jelly on the ascitic hepatoma cell H 22 . Methods: Mice bearing H 22 tumor were fed on different types of royal jelly: No.1, 2 and 3. Their anti tumor effects were observed in vivo . The general royal jelly and normal saline were observed as control. Results: Among these biotic royal jelly, the biotic royal jelly No.1 showed obvious tumor inhibiting and survival prolonging effects. In addition, it increased the number of WBC and augmented the amount of IL 2 and IFN ?; the pathological study also indicated the denaturing and necrosis of most tumor cells with nuclei constraining and cell membrane rupturing, and large amount of lymphocytes and plasmacytes infiltrating around the mass. Conclusion: The No.1 biotic royal jelly has obvious anti tumor effect, and it may take effects by inhibiting or killing tumor cells and improving the immunity of the host. [
