Protective effect of extracts of ginkgo biloba leaves on apoptosis inneuronal cells
- VernacularTitle:银杏叶提取物对神经细胞凋亡的保护作用
- Author:
Yan ZHANG
;
Liang MING
;
Jing_Pei LI
;
Wei_Ping LI
;
Ming FANG
;
- Publication Type:Journal Article
- Keywords:
ginkgo biloba leaves;
neuronal cell;
apoptosis of cell
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study the effect of extracts of ginkgo biloba leaves(GbE) on apoptosis in neuronal cells. Methods Primary cerebral cultures from rat fetus were used to observe the activity of neuronal cells and to determine the release of LDH and DNA gel electrophoresis.Results GbE enhanced the activity of neuronal cells, decresed the release of LDH,and relieved the structural changes of nucleus and DNA fragmentation. Conclusion GbE can inhibit apoptosis in neuronal cells.
