Effects of glipizide and metformin on serum insulin-like growth factor-1,2 in patients with type Ⅱ diabetes mellitus
- VernacularTitle:格列嗪及二甲双胍对Ⅱ型糖尿病人血清胰岛素样生长因子-1,2的影响
- Author:
Jian_Hao PEI
;
Hua_Zhang YANG
;
Jian KUANG
;
Xiao_Zhen LIAO
;
Chong CHENG
;
Hong_Mei CHENG
;
Zhong_Wen LI
;
Yan_Tang CUI
;
- Publication Type:Journal Article
- Keywords:
insulin_like growth factor;
type Ⅱ diabetes mellitus;
glipizide;
metformin
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study the effects of glipizide and metformin on the serum IGF_1,IGF_2 in patients with type Ⅱ diabetes mellitus;Methods The effect of glipizide(n=40) and metformin(n=25) on serum IGF_1,IGF_2 in patients with type Ⅱ diabetes mellitus were compared with self_ controlled study.Results In metformin_treated patients ,there were not significantly changes in fasting IGF_1 and IGF_2 concentrations,In glipizide_treated patients,there were markedly increased IGF_1 concentrations (181.8?104.5) vs (209.0?88.2) ng?ml-1(P
