Protective effects of trigonella foenum graecum L.on acute cerebral ischemia
- VernacularTitle:胡芦巴总皂苷对脑缺血保护作用
- Author:
Linlin LI
;
Xinjian RAN
;
Xinmin MAO
;
Xuefei WANG
;
Jie ZHANG
;
Fei WANG
;
- Publication Type:Journal Article
- Keywords:
cerebral ischemia;
coagulation time;
platelets aggregation;
blood viscosity
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
S AIM To study the protective effects of trigonella foenum graecum(TFGs) on acute cerebral ischemia. METHODS Acute incomplete ischemia was induced by ligaturing bilateral carotid arterise and cutting heads in mice, the survival time and asthmatic time were observed; the coagulation time was measured by sheet glass method,and the blood viscosity was also assayed; the platelet aggregation induced by collagen were studied by turbdimetry in vitro . RESULTS TFGs prolonged survival time, coagulation time and asthmatic time significantly and inhibited platelet aggregation ratio in rabbit,and decreased the blood viscosity. CONCLUSION TFGs has the protective effects on acute cerebral ischemia.
