Detecting melatonin receptor in thyroid of human embryo with immunohistochemistry and in situ hybridization
- VernacularTitle:用原位杂交及免疫组化方法显示人胚胎甲状腺褪黑素受体
- Author:
Zhongan SUN
;
Zuqian LU
;
Zhimin LIU
;
- Publication Type:Journal Article
- Keywords:
receptor, melatonin;
thyroid;
in situ hybridization;
immunohistochemistry
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To make it clear whether there exists melatonin receptor in the thyroid of human embryo. Methods: Thyroid was collected and sliced up to be stained with methods of immunohistochemistry and in situ hybridization. Results: The thyroid tissue was positively dyed, melatonin receptor mt 1 and MT 2 were with both immunohistochemistry and in situ hybridization while brown granules deposited in the membrane, plasma and nuclear of the thyroid cell were with the immunohitochemistry. Conclusion: There exists melatonin receptors in human embryo thyroid, either mt 1 or MT 2, and they exist in the membrane, plasma and nuclear.