Remodeling of retinal microvessels in STZ-induced diabetic rats and medical influence
- VernacularTitle:糖尿病大鼠视网膜微血管的重建及某些药物对其的影响
- Author:
Zhiyong LIU
;
Lirong HAN
;
Chuansen ZHANG
;
Chuangui HAN
;
- Publication Type:Journal Article
- Keywords:
diabetes;
retina;
vascular remodeling;
nonenzymatic glycosylation
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the remodeling of diabetic microvessels in diabetic rats. Methods: Diabetic animal models were induced by STZ on SD rats. The rats were treated with nonenzymatic glycosylation inhibitor and blood flow activating and stasis removing traditional Chinese medicine to evaluate the remodeling of diabetic retinal microvessels by trypsin digestion and figure analysis. Results: At 8 weeks, significant alteration of retinal capillary width in diabetic rats were observed( P