Relation between alteration in myocardium chymase-like activity and cardiac hypertrophy in pressure-overload hypertrophy rats
- VernacularTitle:大鼠压力负荷性心肌肥厚与心脏糜酶样活力改变
- Author:
Hui LI
;
Shisen JIANG
;
Ruihua CHEN
;
- Publication Type:Journal Article
- Keywords:
cardiac hypertrophy;
chymase like activity;
ra\
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the relationship between myocardium chymase like activity and cardiac hypertrophy. METHODS The model of pressure overload hypertrophy was eatablished in rats. The changes of the HW/BW and LVH/BW and myocardium chymase like activity were investigated in the two groups of rats. RESULTS In cardiac hypertrophic rats 2,6,12 weeks after operation,the HW/BW and LVH/BW and myocardium chymase like activity were all significantly increased ( P
