EFFECT OF BILIRUBIN ON THE FUNCTIONAL CHANGES OF SARCOPLASMIC RETICULUM INDUCED BY ACUTE EXERCISE
- VernacularTitle:胆红素对急性运动所致肌质网某些功能改变的影响
- Author:
Chunhua HAN
;
Qien WANG
;
Sheng WANG
;
- Publication Type:Journal Article
- Keywords:
acute exercise;
bilirubin;
sarcoplasmic reticulum
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of bilirubin on the functional changes of sarcoplasmic reticulum (SR) induced by acute exercise. [WT5FZ]Methods:[WT5BZ] 41 Wistar male rats were divided into five groups, control group, exercise group, exercise recovery group, bilirubin treated exercise group and bilirubin treated exercise recovery group. The rats were administered with 1 ?mol/kg body weight of bilirubin or saline once every day for 4 weeks. After swimming with load for 2 h, all of the rats were killed and several indices were determined. [WT5FZ]Results:[WT5BZ] Bilirubin could inhibit the decrease of Ca 2+ content and the increase of Ca 2+ ,Mg 2+ ATPase activity in SR induced by acute exercise, and inhibit the increase of Mg 2+ content in cytoplasm. [WT5FZ]Conclusion:[WT5BZ] Bilirubin may delay the development of fatigue induced by acute exercise through protecting certain functions of SR.
