Roles of NMDA receptors in arterial baroreceptor reflex in rostral ventrolateral medulla of rats
- VernacularTitle:大鼠头端延髓腹外侧区 NMDA受体在动脉压力感受器反射中的作用
- Author:
Zhenxiang XIAO
;
Weizhong WANG
;
Shanfen SHI
;
Hui CHEN
;
Gang SUN
;
- Publication Type:Journal Article
- Keywords:
receptors, N methyl D aspartate acid;
rostral ventrolateral medulla;
arterial baroreceptor refl
- From:
Academic Journal of Second Military Medical University
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the roles of N methyl D aspartate acid (NMDA) receptors of glutamate in mediating the arterial baroreceptor reflex (ABR)in rostral ventrolateral medulla (RVLM) in rats. Methods: The blood pressure, heart rates and ABR were observed after the bilateral microinjection of 0.1 ?l 50 mmol/L ketamine into RVLM of ureth anesthetized rats. Results: Bilateral microinjection of ketamine into RVLM induced decrease of the blood pressure and heart rate ( P
